Tottenham XI: Vicario, Porro, Romero, van de Ven, Udogie, Bissouma, Sarr, Kulusevski, Maddison, Johnson, Son.
Subs: Austin, Hojbjerg, Dragusin, Royal, Werner, Lo Celso, Bentancur, Davies, Scarlett.
Ange Postecoglou has made three changes from the Tottenham side that beat Crystal Palace 3-1 last weekend.
Pedro Porro makes his return at right-back after missing a month with a muscle injury, while Brennan Johnson and Pape Matar Sarr are the others brought in.
Emerson Royal, Rodrigo Bentancur and Timo Werner all drop to the bench.