The easy part is in goal – Robert Sanchez is number one without question.
At right back, with both Reece James and Malo Gusto out, we assume Axel Disasi will step in.
Thiago Silva, despite recent criticism, will continue in the middle, likely alongside Benoit Badiashile, who was given a first league start of the season against Newcastle.
Marc Cucurella is out suspended, so we expect Levi Colwill to play at left back.
The midfield should sort itself out, Moises Caicedo got a break last week, Enzo Fernandez and Conor Gallagher will complete the midfield 3 which was starting to really look solid before the defeat for Newcastle.
Cole Palmer and Raheem Sterling are no brainers to play out wide given their recent form, and that leaves just one space – up front.
There’s a tough call between Nicolas Jackson and Armando Broja. After some disappointing showings from Jackson, we think that Broja will get a chance on this occasion as Mauricio Pochettino looks to shake his team up.